Application of fuzzy control to industrial bioprocesses in Japan

Jun-Ichi Horiuchia; ∗ , Michimasa Kishimotob
a Department of Chemical System Engineering, Kitami Institute of Technology, 165 Koen-cho, Kitami-shi, Hokkaido 090-8507, Japan
b Department of Biotechnology, Graduate School of Engineering, Osaka University, Yamada-oka 2-1, Suita-shi, Osaka, 565-0871, Japan
Received 14 December 1999; received in revised form 1 August 2000; accepted 29 August 2000

Applications of fuzzy control to industrial biological processes in Japan were summarized, compared and discussed in terms of the system features, control purpose, input and output variables, development of fuzzy rules and its e ectiveness. Fuzzy control was mainly applied to the fed-batch cultures of microorganisms and used for the on-line control of feeding rate of substrate. Most of the control systems were developed based on the knowledge of experienced. Fuzzy control is regarded as a promising method for automating the bioprocesses where the experienced operators play signiÿcant roles for their successful operation. c 2002 Elsevier Science B.V. All rights reserved.

Keywords: Fuzzy control; Fermentation process; Bioprocess; Industrial application

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